ShortInterestHistory.com

PRME Short Interest History

Prime Medicine, Inc. Common St | PRME | Nasdaq | Latest report: February 27, 2026

Current Short Interest27.2M
Prior Short Interest28.1M
Change Shares-832.5K
Change %-3.0%
Average Daily Volume3.0M
Days to Cover9.16

Prime Medicine, Inc. Common St (PRME) reported short interest of 27,246,340 shares for the settlement date of February 27, 2026. The prior report showed 28,078,872 shares. That was a change of -832.5K shares, while the latest days-to-cover reading came in at 9.16 using reported average daily volume of 3.0M.

This page tracks 78 reported short interest entries for PRME from October 31, 2022 through February 27, 2026. Over that period, reported short interest ranged from 445.1K to 28.1M shares.

Reported short interest can change for many reasons, including shifts in sentiment, trading activity, and company-specific events.

Download last 6 months as CSV

Short Interest Over Time

Days to Cover Over Time

Extreme edge-case readings may reflect unusually low reported average volume.

Short Interest History for PRME

Settlement DateShort InterestPrior Short InterestChange SharesChange %Average Daily VolumeDays to Cover
February 27, 202627,246,34028,078,872-832.5K-3.0%3.0M9.16
February 13, 202628,078,87227,079,706999.2K+3.7%2.6M10.93
January 30, 202627,079,70626,301,427778.3K+3.0%2.9M9.23
January 15, 202626,301,42725,672,632628.8K+2.5%3.6M7.3
December 31, 202525,672,63221,886,4083.8M+17.3%4.1M6.26
December 15, 202521,886,40819,673,4662.2M+11.2%3.4M6.35
November 28, 202519,673,46618,603,3741.1M+5.8%3.9M5.01
November 14, 202518,603,37418,214,907388.5K+2.1%3.8M4.86
October 31, 202518,214,90715,774,1562.4M+15.5%3.8M4.85
October 15, 202515,774,15620,012,461-4.2M-21.2%4.7M3.35
September 15, 202519,119,42919,248,932-129.5K-0.7%2.9M6.69
August 29, 202519,248,93218,372,361876.6K+4.8%2.8M6.97
August 15, 202518,372,36121,851,787-3.5M-15.9%4.3M4.3
July 31, 202521,851,78721,664,197187.6K+0.9%4.9M4.5
July 15, 202521,664,19720,144,9171.5M+7.5%6.5M3.35
June 30, 202520,144,91718,480,7031.7M+9.0%4.3M4.67
June 13, 202518,480,70317,966,546514.2K+2.9%1.9M9.65
May 30, 202517,966,54617,703,437263.1K+1.5%3.5M5.17
May 15, 202517,703,43716,526,5961.2M+7.1%1.4M12.73
April 30, 202516,526,59616,692,858-166.3K-1.0%1.5M10.77
April 15, 202516,692,85818,302,982-1.6M-8.8%1.8M9.24
March 31, 202518,302,98219,406,034-1.1M-5.7%1.5M12.51
February 28, 202518,042,94218,059,532-16.6K-0.1%1.1M16.56
February 14, 202518,059,53217,302,954756.6K+4.4%1.1M15.83
January 31, 202517,302,95417,209,99293.0K+0.5%726.4K23.82
January 15, 202517,209,99216,939,183270.8K+1.6%888.6K19.37
December 31, 202416,939,18316,129,538809.6K+5.0%1.3M13.07
December 13, 202416,129,53815,761,230368.3K+2.3%1.1M14.24
November 29, 202415,761,23015,189,710571.5K+3.8%1.3M12.53
November 15, 202415,189,71015,794,961-605.3K-3.8%1.1M13.92
October 31, 202415,794,96117,635,877-1.8M-10.4%1.1M15.02
October 15, 202417,635,87716,715,788920.1K+5.5%1.7M10.12
September 30, 202416,715,78816,573,943141.8K+0.9%3.7M4.53
September 13, 202416,573,94316,266,975307.0K+1.9%610.4K27.15
August 30, 202416,266,97515,894,539372.4K+2.3%440.6K36.92
August 15, 202415,894,53914,914,710979.8K+6.6%690.4K23.02
July 31, 202414,914,71013,716,2641.2M+8.7%645.9K23.09
July 15, 202413,716,26412,708,2081.0M+7.9%719.9K19.05
June 28, 202412,708,20811,569,7401.1M+9.8%1.3M9.8
June 14, 202411,569,74011,453,291116.4K+1.0%887.9K13.03
May 31, 202411,453,29111,251,663201.6K+1.8%1.0M11.18
May 15, 202411,251,66310,877,686374.0K+3.4%812.3K13.85
April 30, 202410,877,68610,213,643664.0K+6.5%879.8K12.36
April 15, 202410,213,6439,923,829289.8K+2.9%789.0K12.94
March 28, 20249,923,8299,666,173257.7K+2.7%441.4K22.49
March 15, 20249,666,1739,222,470443.7K+4.8%584.3K16.54
February 29, 20249,222,47010,345,100-1.1M-10.8%754.0K12.23
February 15, 202410,345,1009,109,8801.2M+13.6%909.4K11.38
January 31, 20249,109,8808,093,2651.0M+12.6%603.1K15.1
December 29, 20237,344,0527,347,354-3.3K-0.0%365.9K20.07
December 15, 20237,347,3547,055,814291.5K+4.1%718.2K10.23
November 30, 20237,055,8147,334,366-278.6K-3.8%519.4K13.59
November 15, 20237,334,3667,613,977-279.6K-3.7%582.9K12.58
October 31, 20237,613,9777,561,71852.3K+0.7%562.7K13.53
October 13, 20237,561,7187,502,29459.4K+0.8%467.0K16.19
September 29, 20237,502,2945,499,8972.0M+36.4%293.5K25.56
September 15, 20235,499,8975,090,418409.5K+8.0%731.5K7.52
August 31, 20235,090,4185,070,34920.1K+0.4%188.7K26.98
August 15, 20235,070,3494,794,695275.7K+5.8%289.5K17.51
July 31, 20234,794,6955,432,357-637.7K-11.7%254.8K18.82
July 14, 20235,432,3575,437,366-5.0K-0.1%240.8K22.56
June 30, 20235,437,3663,597,8911.8M+51.1%892.4K6.09
June 15, 20233,597,8913,738,468-140.6K-3.8%447.9K8.03
May 31, 20233,738,4684,046,603-308.1K-7.6%271.7K13.76
May 15, 20234,046,6033,990,46556.1K+1.4%291.7K13.87
April 28, 20233,990,4653,577,710412.8K+11.5%235.1K16.98
April 14, 20233,577,7102,974,670603.0K+20.3%239.9K14.91
March 31, 20232,974,6702,598,021376.6K+14.5%206.9K14.38
March 15, 20232,598,0212,297,484300.5K+13.1%174.6K14.88
February 28, 20232,297,4842,153,498144.0K+6.7%155.1K14.82
February 15, 20232,153,5062,198,300-44.8K-2.0%170.4K12.64
January 31, 20232,198,3002,220,656-22.4K-1.0%91.1K24.12
January 13, 20232,220,6561,645,596575.1K+35.0%194.8K11.4
December 30, 20221,645,5961,362,910282.7K+20.7%316.8K5.2
December 15, 20221,362,9101,040,793322.1K+30.9%232.2K5.87
November 30, 20221,040,793775,930264.9K+34.1%189.3K5.5
November 15, 2022775,930445,119330.8K+74.3%289.8K2.68
October 31, 2022445,1190445.1K+100.0%636.4K1

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